Flights at Gatwick Airport were cancelled, delayed or diverted at short notice on Thursday due to a shortage of air traffic controllers.
Gatwick confirmed 22 cancellations as of 22:00 BST, while the website FlightRadar24 said hundreds of flights in and out of the airport were delayed.
The National Air Traffic Services (Nats) apologised for its staffing shortages.
Gatwick Airport said it expected a normal service on Friday.
The disruption comes just over two weeks after a technical issue at Nats led to 2,000 flights being cancelled across the UK.
EasyJet expressed frustration at Thursday's delays and cancellations, while Ryanair boss Michael O'Leary called on Nats' boss to resign.
Mr O'Leary said: "It is unacceptable that more flights and hundreds of passengers are suffering delays to/from Gatwick Airport due to Nats CEO, Martin Rolfe's blatant failure to adequately staff UK ATC.
"Airlines are paying millions of pounds to Nats each and every year and should not have to see their passengers suffer avoidable delays due to UK ATC staff shortages."
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